All of the following DSM-5 criteria should be met for narcolepsy patients. The following criteria should be met for narcolepsy type 2 patients.
Cataplexy and a positive multiple sleep latency test.
Diagnostic criteria for narcolepsy. Two tests that are considered essential in confirming a diagnosis of narcolepsy are the polysomnogram PSG and the multiple sleep latency test MSLT. On the basis of the ICSD clinical criteria we proposed to adopt the following diagnostic classification. Narcolepsy is a neurological sleep disorder that causes a potentially disabling level of daytime sleepiness.
Low or absent CSF hypocretin-1 levels CSF hypocretin-1 concentration measured by immunoreactivity is either 110 pgmL or. The overnight polysomnogram PSG and Multiple sleep latency test MSLT are still the gold standards for diagnosing narcolepsy. To receive an official diagnosis of type 1 narcolepsy a person must meet the following criteria.
Narcolepsy should be diagnosed only if the individual has demonstrated a regular sleep-wake schedule with an adequate amount of nocturnal sleep. The Diagnostic and Statistical Manual of Mental Disorders Fifth Edition DSM-5 defines narcolepsy as recurrent episodes of irrepressible need to sleep lapsing into sleep or napping occurring. How narcolepsy type 2 is diagnosed according to the American Academy of Sleep Medicine AASM ICSD-3 criteria.
Hypocretin levels at less than one-third of baseline normal levels. 1 Recurrent periods of an irrepressible need to sleep lapsing into sleep or napping occurring within the same day. Cataplexy brief bilateral loss of muscle tone.
Formal diagnosis requires staying overnight at a sleep center for an in-depth sleep analysis. Research has shown that measuring the level of hypocretin in your cerebrospinal fluid which surrounds the brain and spinal cord can be useful in diagnosing narcolepsy. To measure your level of hypocretin a sample of cerebrospinal fluid is removed using a needle during a procedure called a lumbar puncture.
Sleep deprivation and irregular sleep schedules may rarely lead to sleep-related hallucinations or sleep paralysis but not to cataplexy. And one of the following. The patient has daily periods of irrepressible need to sleep or.
If narcolepsy type 1 is strongly suspected clinically but MSLT criteria are not met consider repeating the MSLT. Stimulants should be stopped the week before this testing and antidepressant medications should be stopped 2 to 3 weeks prior. Parkinson disease myotonic dystrophy tumors or infiltrative disorders such as sarcoidosis involving the hypothalamus autoimmune or paraneoplastic conditions with anti-Ma-2 or anti-aquaporin-4 antibodies multiple sclerosis Prader-Willi syndrome and head trauma.
This sleepiness may occur in the form of repeated and irresistible sleep attacks In these episodes a person suddenly falls asleep in unusual situations such as while eating walking or driving. How narcolepsy is diagnosed according to the American Psychiatric Association APA DSM-5 criteria. The limitations of current diagnostic criteria for narcolepsy are discussed and a possible new classification system incorporating the borderland conditions is presented.
If narcolepsy type 1 is strongly suspected clinically but the MSLT criteria of B1 are not met a possible strategy is to repeat the MSLT. The only clinical manifestation that is specific to narcolepsy is cataplexy. Disease onset is usually in the second decade of life.
The classic tetrad of narcolepsy seen in only 10 to 15 of cases includes excessive daytime sleepiness cataplexy sleep paralysis and hypnagogichypnopompic hallucinations. Diagnostic Criteria Criteria A-E must be met A. Possible narcolepsy in the.
Finally advances and obstacles in the symptomatic and causal treatment of narcolepsy are reviewed. Three months of excessive daytime sleepiness that cannot be explained by another health condition or medication use. Formal diagnosis criteria for narcolepsy requires a patient to take part in a sleep study which involves staying overnight in a sleep center where doctors can monitor you to determine what if any sleep disorder you may be suffering from You will be required to provide a detailed sleep history and keep and ongoing sleep journal outlining your sleep habits.
Your doctor may make a preliminary diagnosis of narcolepsy based on your excessive daytime sleepiness and sudden loss of muscle tone cataplexy. Ascertained narcolepsy in the presence of criteria B recurrent daytime naps or lapses into sleep that occur almost daily for at least three months and C sudden bilateral loss of postural muscle tone in association with intense emotion -cataplexy -. Type 1 Narcolepsy Diagnostic Criteria.
The PSGMSLT should be preceded by at least one week of actigraphic recording or a sleep log. Diagnosis of Narcolepsy and Testing. G47419 Alternate Names Narcolepsy without cataplexy.
The standard for the diagnosis of narcolepsy involves an overnight sleep study called a polysomnogram followed by a multiple sleep latency test MSLT the next day. In addition one or more of the following signs is required to achieve any diagnosis of narcolepsy. 1 The patient has daily periods of irrepressible need to sleep or lapses into daytime sleep occurring for at least 3 months1.
Type 2 Narcolepsy Diagnostic Criteria. After an initial diagnosis your doctor may refer you to a sleep specialist for further evaluation. In addition questionnaires such as the.
All criteria for narcolepsy type 2 PLUS disease are likely attributable to another medical disorder. All of these categories require the main narcolepsy symptom of excessive daytime sleepiness EDS occurring at least three times per week for at least three weeks.
